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下肢静脉性溃疡(VLU)是血管外科常见的疾病,其多迁延不愈,愈后易复发,现今仍然是临床上颇为棘手的难题.现有的治疗方法可分为保守治疗和手术治疗两大类,笔者概述其药物治疗、压力治疗、传统手术、腔内和腔镜手术以及针对穿通静脉和溃疡面处理等方法的进展,以期为临床上以外科手术为主的VLU综合治疗方法提供借鉴.“,”Venous leg ulcer (VLU) is a common disease in the field of vascular surgery, and is still a challenge in clinical practice due to its often delayed healing and frequent recurrence after healing. The current therapeutic options for VLU mainly include conservative treatment and surgical intervention. Here, the authors address the progress with regard to its drug therapy, compression therapy, traditional surgery, and endovascular and endoscopic treatment as well as managements for the perforator veins and wound surface, so as to provide reference for the surgery-based comprehensive treatment of VLU in clinical practice.