青壮年猝死综合征(SMDS)一直是国内外医学界尤其是法医学领域研究的热点,近来对SMDS的发病特点及致病机制等都有广泛而深入的研究,但仍有部分关键问题尚未解决。本文通过文献复习并结合法医检案,分别从分子遗传学、免疫组织化学、冠状动脉结构或功能异常、自主神经调节作用等方面介绍SMDS的研究进展。 Sudden death syndrome (SMDS) has always been a hot spot in the field of medical science, especially forensic science both at home and abroad. Recently, the study on the pathogenesis and pathogenesis of SMDS has been extensive and in-depth study, but some of the key issues remain unresolved. This article reviewed the literature and combined with forensic medical records, respectively, from the molecular genetics, immunohistochemistry, coronary artery structure or dysfunction, autonomic regulation, and so on SMDS research progress.