Precuneus contributes to attentive control of finger movement

来源 :Acta Pharmacologica Sinica | 被引量 : 0次 | 上传用户:wsz2228507
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AIM: To examine whether precuneus subserves the attentive control of finger movement or whether it mediates themovement preparation and motor inhibition. METHODS: In the Preparation Stage, subjects were shown with a 5-number string in which each number stood for a key-pressing response, the number strings included a complexpattern (eg, 4-1-4-2-3), or a simple one (eg, 2-2-2-2-2), or a null one (ie, x-x-x-x-x). In the Execution Stage, fivereaction signs were presented one by one and subjects were required to press the corresponding key to each signsequentially (eg, in the 4-1-4-2-3 preparation example, subjects press key 4 to the first sign, press key 1 to thesecond sign, key 4 to the third sign and so on). For the null preparation pattern, five numbers, rather than thereaction signs, were shown at the same pace as in the other two conditions and subjects were to press the corre-sponding keys. RESULTS: Left medial frontal gyrus (BA 6) and precentral gyrus (BA 6) were involved in both ofthe Preparation Stage and the Execution Stage, whereas left precuneus (BA 7) was activated only in the ExecutionStage. CONCLUSION: Precuneus mediates the attentive control of finger movement, but not the movementpreparation or motor inhibition. AIM: To examine whether precuneus subserves the attentive control of finger movement or whether it mediates themovement preparation and motor inhibition. METHODS: In the Preparation Stage, subjects were shown with a 5-number string in which each number stood for a key-pressing response , the number strings included a complex pattern (eg, 4-1-4-2-3), or a simple one (eg, 2-2-2-2-2), or a null one (ie, xxxxx). In the Execution Stage, fivereaction signs were presented one by one and subjects were required to press the corresponding key to each sign sequenced (eg, in the 4-1-4-2-3 preparation example, subjects press key 4 to the first sign, press key 1 to thesecond sign, key 4 to the third sign and so on). For the null preparation pattern, five numbers, rather than thereaction signs, were shown at the same pace as in the other two conditions and subjects were to press the corre -sponding keys. RESULTS: Left medial frontal gyrus (BA 6) and precentral gyrus (BA 6) were involved in bot h of the Preparation Stage and the Execution Stage, while left precuneus (BA 7) was activated only in the Execution Stage. CONCLUSION: Precuneus mediates the attentive control of finger movement, but not the movement preparation or motor inhibition.
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