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目的了解十堰市健康人群流行性脑脊髓膜炎(流脑)带菌状况及菌群分布,为合理制定有效的预防措施提供依据。方法于每年流行前期(10—12月份),随机采集健康人群咽拭子,接种卵黄双抗琼脂平板分离培养,并挑取疑似菌落进行染色镜检、生化鉴定及血清分型。结果2004—2007年健康人群流脑总带菌率为2.90%(35/1206),以B群为主,B群带菌率为1.57%(19/1206),各年龄组人群流脑带菌差异有统计学意义(P<0.01),性别无显著差异(P>0.05)。结论十堰市健康人群带菌率较低,带菌菌群以B群为主,A群次之。高中生和福利院老人健康带菌率较高,应作为流脑重点防控人群,加强流脑疫苗预防接种和病源学监测。
Objective To understand the prevalence and distribution of epidemic cerebrospinal meningitis (CSF) in healthy population in Shiyan and to provide a basis for the reasonable formulation of effective preventive measures. Methods Throat swabs from healthy population were collected randomly from January to December each year. The swabs were inoculated with YBD agar plates, and the suspected colonies were picked for microscopic examination, biochemical identification and serotyping. Results In 2004-2007, the prevalence rate of total meibugam in healthy population was 2.90% (35/1206), with B group as the mainstay, B group with 1.57% (19/1206) Significance (P <0.01), no significant gender differences (P> 0.05). Conclusion The population of healthy people in Shiyan City is relatively low with group B as the main carrier and group A as the second. High school students and welfare homes for the elderly with higher rates of health, should focus on prevention and control of people with meningitis, and strengthen the prevention of meningitis vaccination and etiology monitoring.