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目的分析我院药品不良反应(ADR)发生的一般规律和特点。方法对医院2013年1~12月收集的312例ADR报告进行统计、分析。结果 60岁以上人群发生的ADR为98例(占31.41%);静脉给药引起的ADR255例(占81.73%);引起ADR的药品共15类115种,抗菌药物居首位,为137例(占43.91%);ADR类型主要表现为皮肤及其附件损害(121例,占38.78%);严重ADR 27例,占8.65%。结论临床重视和加强ADR的监测工作,能有效的减少ADR的发生。
Objective To analyze the general rules and characteristics of adverse drug reaction (ADR) in our hospital. Methods The data of 312 ADR cases collected in the hospital from January to December in 2013 were analyzed. Results There were 98 ADR cases (accounting for 31.41%) in 60 years old and above; ADR255 cases (81.73%) caused by intravenous administration; 115 kinds of 15 kinds of drugs causing ADR, antimicrobial drugs topped 137 cases Accounting for 43.91%). ADR types mainly manifested damage to the skin and its appendages (121 cases, accounting for 38.78%); severe ADR 27 cases, accounting for 8.65%. Conclusion Clinical attention and strengthening of the monitoring of ADR can effectively reduce the occurrence of ADR.