放射性微球内放射治疗是肝脏恶性肿瘤的一种有效可行的非手术疗法.目前理想的放射性核素为~(90)Y及~(32)P,其中~(90)Y由于能量高,半衰期较短,一直为大家所采用.微球材料较有发展前途的是能将核素包在微球本身的生物不降解微球,如玻璃微球,其直径多为15～35μ.~(90)Y微球经肝动脉导管注入肝脏,常用临床剂量以50～100Gy为全肝平均吸收剂量.肿瘤富血管者疗效好,有胃肠道显像及明显肝-肺分流者为该疗法的禁忌症. Radioactive intracellular radiation therapy is an effective and feasible non-surgical therapy for malignant tumors of the liver. The current ideal radionuclides are ~(90)Y and ~(32)P, in which ~(90)Y is due to high energy, half-life. Shorter, it has been adopted by everyone. Microsphere materials have a promising future. They are biodegradable microspheres that can enclose the radionuclides in the microspheres themselves, such as glass microspheres, which have a diameter of 15~35μ.~(90). ) Y microspheres are injected into the liver through hepatic artery catheters, and the commonly used clinical dose is 50 to 100 Gy as the average absorbed dose of the whole liver. Tumor-rich patients have good curative effects, and there are gastrointestinal tract imaging and obvious liver-pulmonary shunts. disease.