目的探讨高频超声检测乳腺肿块内微钙化灶在乳腺癌诊断中的应用价值。方法对112例合并钙化的乳腺肿块患者进行高频超声检测，重点观察肿块内钙化灶大小、形状、数目及分布特征，以术后病理为诊断“金标准”，比较分析乳腺肿块内不同钙化类型与肿块良恶性之间的关系。结果术后病理证实：112例肿块中恶性79例，良性33例。乳腺恶性肿块合并钙化(70.54%，79/112)较良性肿块合并钙化(29.46%，33/112)多见；恶性肿块微钙化发生率(92.41%)明显高于良性肿块(30.30%)。恶性肿块微钙化以簇状分布为主(69.86%)。微钙化灶诊断乳腺恶性肿瘤的敏感度为92.41%。结论高频超声能有效显示乳腺肿块内部微钙化灶类型，呈簇状分布的微钙化灶是高频超声诊断乳腺癌的重要指标。“,” Objective To explore the diagnosis value of the high-frequency ultrasonography in breast cancer with micro-calcification. Methods 112 cases of breast mass with calcification were tested by high-frequency ultrasonography,which confirmed by postoperative pathology. Emphasis was placed on the size, shape, number and distribution of the calcifications within the mass. And to analysis of the relationship between the calcification types and the nature of the mass. Results 79 of 112 cases were malignant and 33 of 112 cases were benign. Malignant mass with calcification(70.54%, 79/112) were more common than that of benign mass(29.46%, 33/112). The incidence of micro-calcification in malignant mass(92.41%) was significantly higher then benign mass(30.30%). The clusters of micro-calcifications(69.86%) was the main distribution types in malignant mass. The diagnostic sensitivity of breast cancer by microcalcifications was 92.41%. Conclusions High-frequency ultrasonography can effectively display the type of micro-calcifications in the breast mass. The clusters of micro-calcifications is an important index of breast cancer in high-frequency ultrasonography.