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目的探讨奥美拉唑联合克拉霉素,阿莫西林治疗口周皮炎的疗效。方法 90例口周皮炎患者随机分为两组,两组均外涂氯硫霜,3次/d。同时,治疗组口服奥美拉唑及克拉霉素,阿莫西林,两组疗程均为10天,疗程结束后随访6个月,判定疗效并观察复发率。结果治疗组有效率为89.13%,对照组为63.64%;治疗组复发率为11.11%,对照组为83.33%。两组有效率及复发率差异均有统计学意义(P均<0.005)。结论奥美拉唑联合克拉霉素、阿莫西林治疗口周皮炎疗疗效显著,复发率低。
Objective To investigate the efficacy of omeprazole combined with clarithromycin and amoxicillin in the treatment of oral dermatitis. Methods 90 patients with perioral dermatitis were randomly divided into two groups, two groups were coated with chlorine sulfur cream, 3 times / d. At the same time, omeprazole, clarithromycin and amoxicillin were given orally in the treatment group. The two courses of treatment were both 10 days. After the course of treatment was followed up for 6 months, the curative effect was observed and the recurrence rate was observed. Results The effective rate was 89.13% in the treatment group and 63.64% in the control group. The recurrence rate was 11.11% in the treatment group and 83.33% in the control group. The difference between the two groups was statistically significant (P <0.005). Conclusion omeprazole combined with clarithromycin, amoxicillin in the treatment of perioral dermatitis significant effect, the recurrence rate is low.