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目的探讨胰腺癌肝转移治疗的有效方法。方法采用区域性动脉灌注化疗与癌内注射疗法治疗不能切除胰腺癌肝转移的患者。结果术中癌内直接注射5─FU8例，注射无水酒精3例。术后动脉灌注化疗5─FU、DDP、ADM共25个周期。11例患者均无治疗相关并发症，平均生存期11．4±8．7（5～36）月。其中1例术后7个月再手术行胰十二指肠切除，随访29月无复发。结论该方法用于不能切除胰腺癌肝转移的治疗，有助于改善患者的生存期，是一种安全有效的方法。
Objective To explore an effective method for liver metastasis of pancreatic cancer. Methods Regional arterial infusion chemotherapy and intratumoral injection therapy were used to treat patients with unresectable pancreatic liver metastases. Results Intraoperative injection of 5-FU in cancer was performed directly in 8 patients and absolute alcohol was injected in 3 patients. Postoperative arterial infusion chemotherapy included 25 cycles of FU, DDP, and ADM. None of the 11 patients had treatment-related complications and the average survival time was 11.4±8.7 (5 to 36) months. One patient underwent reoperation for pancreaticoduodenectomy at 7 months postoperatively, and there was no recurrence at 29 months of follow-up. Conclusion This method is a safe and effective method for the treatment of pancreatic cancer without liver metastasis, which is helpful to improve the survival of patients.