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目的探讨高频电波刀宫颈环切术(1oop electrosurgical excision procedure,Leep)治疗宫颈上皮内瘤样病变(Cervical Intraepithelial Neoplasia,CIN)的临床效果。方法经宫颈细胞学检查和阴道镜下多点活检病理诊断为CIN的患者120例进行回顾性研究,随机分成Leep治疗组(80例)及激光对照组(70例),比较两组手术时间、术中出血量、治愈率及术后并发症。结果二者在手术时间、术中出血,Leep组明显优于激光组(P<0.01);术后半年治愈率Leep组96.52%(77/80),激光对照组97.14%(68/70),差异无显著性(P>0.05)。结论Leep刀治疗优于激光治疗,是治疗CIN的有效方法,对其可靠性尚待进一步研究。
Objective To investigate the clinical effect of 1oop electrosurgical excision procedure (Leep) on cervical intraepithelial neoplasia (CIN). Methods A total of 120 patients with cervical intraepithelial neoplasia (CIN) diagnosed by cervical cytology and colposcopy biopsy were retrospectively studied. They were randomly divided into two groups: the Leep group (80 cases) and the laser control group (70 cases). The operative time, Intraoperative blood loss, cure rate and postoperative complications. Results Both of them had hemorrhage during operation and intraoperatively, and the Leep group was significantly better than the laser group (P <0.01). The half-year cure rate was 96.52% (77/80) in the Leep group, 97.14% (68/70) in the laser control group, There was no significant difference (P> 0.05). Conclusion Leep knife treatment is superior to laser treatment is an effective method of treatment of CIN, its reliability needs further study.