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本文比较了年轻(3～4月龄)和老龄(20～21月龄)雄性Wistar大鼠全血、肝脏、心脏、肾脏组织硒谷胱甘肽过氧化物酶(SeGSN-P_x)的活性,血浆以及上述脏器组织脂质过氧化物(LPO)的含量及SeGSH-P_x/LPO比值变化。观察给予老龄雄性大鼠机体补充Se后对上述指标的影响。结果表明,Se可以提高老龄机体抗脂质过氧化的能力。
This study compared selenium glutathione peroxidase (SeGSN-P_x) activity in whole blood, liver, heart and kidney of young (3 to 4 months old) and old (20 to 21 months old) male Wistar rats. The content of plasma lipids and lipid peroxides (LPO) in these organs and the ratio of SeGSH-Px/LPO were changed. Observed the effects of selenium supplementation on selenium in aged male rats. The results show that Se can improve the anti-lipid peroxidation ability of the elderly.