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目的 探究个性化护理对乙型肝炎肝硬化失代偿期患者治疗依从性的影响。方法 将我院收治的94例乙型肝炎肝硬化失代偿期的患者纳入研究范围，时间为2017年5月至2019年5月，并应用等量计算机随机的方式对其平均分组，分别应用个性化护理方式进行护理干预（试验组）及常规护理干预方式进行干预（对照组），对比两组的护理效果。结果 试验组患者的治疗依从性显著高于对照组，且生活质量各维度评分均显著高于对照组（P＜0.05）。结论 对易感肝硬化失代偿期患者应用个性化护理方式进行干预，有利于提升患者治疗的依从性，提升预后质量。“,”Objective To explore the effect of personalized nursing on treatment compliance of patients with decompensated hepatitis B cirrhosis.Methods A total of 94 patients with decompensated hepatitis B cirrhosis from May 2017 to May 2019 were enrolled in the study. The patients were randomly divided into two groups by equal amount of computer. Individualized nursing (experimental group) and routine nursing intervention (control group) were used to intervene， and the nursing effect was compared. Results The treatment compliance of the experimental group was significantly higher than that of the control group， and the scores of each dimension of the quality of life in the experimental group were significantly higher than those in the control group (P＜0.05). Conclusion Individualized nursing intervention for patients with susceptible liver cirrhosis in decompensated stage is conducive to improving the patient\'s treatment compliance and prognosis quality.