论文部分内容阅读
目的研究急性胰腺炎大鼠血清瘦素(Leptin)水平在乌司他丁干预下的变化。方法将实验动物分为急性胰腺炎组(A组)、急性胰腺炎乌司他丁治疗组(B组)、空白对照组(C组),采用放射免疫法测定各组大鼠血清瘦素水平的变化。结果A组与B、C组比较,血清瘦素水平差异有统计学意义(P<0.01);B、C组比较,血清瘦素水平差异无统计学意义(P>0.05)。结论急性胰腺炎时存在高瘦素水平,乌司他丁可显著改善大鼠急性胰腺炎的预后。
Objective To study the changes of serum leptin levels in rats with acute pancreatitis under ulinastatin intervention. Methods The experimental animals were divided into acute pancreatitis group (group A), acute pancreatitis ulinastatin group (group B) and blank control group (group C). The levels of serum leptin in each group were measured by radioimmunoassay The change. Results There was significant difference in serum leptin levels between group A and B and group C (P <0.01). There was no significant difference in serum leptin between group B and C (P> 0.05). Conclusions There is high leptin level in acute pancreatitis. Ulinastatin can significantly improve the prognosis of acute pancreatitis in rats.