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Her-2(Human Epithelial Receptor Type 2)作为一种原癌基因参与多种肿瘤的发生发展,中枢神经系统肿瘤亦存在Her-2表达,尤其是恶性脑肿瘤。目前科研工作者对Her-2在中枢神经系统肿瘤进展中的作用机制进行了大量研究,并针对性进行了分子靶向及免疫治疗的研究。本文将从以上方面对Her-2在脑肿瘤方面的研究作以综述。
Her-2 (Human Epithelial Receptor Type 2) is a proto-oncogene involved in the development of many tumors. Her-2 expression also exists in central nervous system tumors, especially in malignant brain tumors. At present, researchers have done a lot of research on the mechanism of action of Her-2 in the progression of central nervous system tumors, and targeted the study of molecular targeting and immunotherapy. This article will review the above studies on Her-2 in brain tumors.