肺癌病人呼气中的挥发性有机化合物

来源 :生物化学与生物物理进展 | 被引量 : 0次 | 上传用户:george_zg
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
早期诊断肺癌用紫外线辅助纤维支气管内窥镜术和细胞学检查法。由于费用昂贵和系创伤性诊断法,难于用作大规模筛选。因此须寻求其他的早期检测方法。应用特殊的呼气收集技术及电子计算机辅助气相色谱/质谱法(GC/MC),已证明肺癌病人呼气中丙酮、甲基乙基酮及正丙醇等若干挥发性有机化合物含量高。用12个肺癌病人的样品和17个正常人对照样品的 GC/MC 描绘图谱经电子计算机统计,发现具有显著 Early diagnosis of lung cancer with UV-assisted fiberoptic bronchoscopy and cytology. It is difficult to use as a large-scale screening because it is expensive and traumatic. Therefore, other early detection methods must be sought. Using special breath collection techniques and computer-aided gas chromatography/mass spectrometry (GC/MC), it has been demonstrated that lung cancer patients have high levels of volatile organic compounds such as acetone, methyl ethyl ketone, and n-propanol. The GC/MC profile of 12 lung cancer patient samples and 17 normal human control samples was statistically calculated by computer and found to be significant.
其他文献