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雄性激素的胸腺效应降低机体的免疫能力,必然提高哺乳动物对电离辐射的敏感性。然而,有关雄性激素的辐射致敏效果和雌性激素的放射防护效果,文献报导是有争论的。本文报导抗维性激素药物——色普龙醋酸酯(1α,2α次甲基氯地孕酮醋酸酯)对小白鼠照前给药的良好预防效果。材料和方法:5周龄雄性小白鼠,每10~20只分为四组,即组①,在第5周去势,结扎输精管,除去睾丸
The thymus effect of androgens reduces the body’s immune capacity and inevitably increases mammalian sensitivity to ionizing radiation. However, literature reports about the radiosensitizing effects of androgen and the radioprotective effects of estrogen are controversial. This article reports the good preventive effect of anti-dimensional sex hormone drug, chlorpronone acetate (1α, 2α methreluate progesterone acetate), on mice before administration. Materials and Methods: 5-week-old male mice, divided into four groups every 10 to 20, namely group 1, castrated in the fifth week, ligating the vas deferens, and removing the testis