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对某化肥厂343名职工肝癌发病情况进行了回顾性队列调查,结果表明:该厂男性肝癌的标化死亡率为134.41/105,SMR=6.72(P<0.01)非常显著,高于我省肝癌死亡率,但女性死亡率未见增加。接触氯化氢等工业毒物的两组职工与非接毒组的职工患肝癌的相对危险度SRR<1,因此认为该厂肝癌高发与该行业HF等毒物接触缺乏明显的联系。本文还对该厂职工乙肝感染、饮酒习惯等对肝癌的影响作了探讨。
A retrospective cohort survey was conducted on the incidence of liver cancer among 343 employees in a chemical fertilizer plant. The results showed that the standardized mortality rate of male liver cancer at the plant was 134.41/105, and SMR was 6.72 (P<0.01). Liver cancer mortality in our province, but no increase in female mortality. Employees exposed to industrial toxicants such as hydrogen chloride had a relative risk of SRR of less than 1 for workers suffering from hepatocellular carcinoma. Therefore, it is believed that the high incidence of liver cancer in this factory is not clearly related to the exposure to toxicants such as HF in the industry. This article also explored the effects of Hepatitis B infection and drinking habits on HCC in workers of the factory.