Objective: To investigate a new method of combined laparoscopy edici ne (CHM) in treating endometrial ovarian cyst. Methods: One hundre d and fifty-two patients with endometrial ovarian cyst three therapies: combined laparoscopy with CHM (combination group), CHM (TCM group) and To compare the clinical efficacy and side-effects shown by the three groups and to elucidate the therapeutic mechanism by ne hormone, plasma prostaglandin F 2α , prostaglandin E 2 etc. Results: The shrinking rate, ate of the cysts and markedly effective rate in the combination group were obviously higher than those in the TCM group and WM bination group was also higher than that of the WM group (P<0.05). Few side-effects constituted age for the combination g roup and TCM group. After treatment, the plasm a prostaglandin F 1α lowered remarkably, serum obviously (P<0. 01, P<0.05). Conclusion: The laparoscopy and CHM combination therapy is a new method in cyst which has signifi cant efficacy, minimal adverse effect and maximal preservation of reproductive function.