为探讨放射治疗中氧效应,在低氧状态下对小鼠一次性照射,计数小肠纵断面隐窝数,观察低氧对小鼠的防护作用。结果为:未受照射的低氧组与空气组的组织学表现或隐窝计数无显著差异,表明短时间单纯吸入低氧(11％)72小时后不会对小肠产生明显影响。5Gy照射后72小时后78％隐窝明显再生,与对照组无明显差异。8Gy,10Gy,12Gy,15Gy,18Gy组与空气对照组都有显著性统计差异。 To investigate the effect of oxygen in radiation therapy, mice were exposed to hypoxia at one time and the number of small intestine longitudinal crypts was counted to observe the protective effect of hypoxia on mice. The results showed that there was no significant difference in the histological appearance or crypt counts between the unirradiated hypoxic group and the air group, indicating that a short-term inhalation of hypoxia (11%) would not have a significant effect on the small intestine after 72 hours. After 72 hours of 5 Gy irradiation, 78% of crypts regenerated significantly, which was not significantly different from the control group. There were statistically significant differences between the 8 Gy, 10 Gy, 12 Gy, 15 Gy, and 18 Gy groups and the air control group.