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本文研究的目的是评价在月经周期的滤泡期给予克罗米芬枸橼酸盐(CC)是否影响妊娠早期卵巢类固醇的分泌。作者研究了12例21~36岁的孕妇,5例(对照组)在妊娠和研究期,除补充铁剂外,未接受任何药物。另外7例(治疗组)从妊娠周期的第1~5天接受CC,以诱发滤泡发育;每天给药50mg(n=2),100mg(n=3)和150mg(n=2)。通过超声波和黄体生成素测定和/或基础体温的变化
The purpose of this study was to evaluate whether clomiphene citrate (CC) administered during the follicular phase of the menstrual cycle affects ovarian steroid secretion during early pregnancy. The authors studied 12 pregnant women between the ages of 21 and 36 years, and 5 (control group) did not receive any medication other than iron supplementation during pregnancy and study period. Another 7 patients (treatment group) received CC from days 1 to 5 of the gestation cycle to induce follicular development; 50 mg (n = 2), 100 mg (n = 3) and 150 mg (n = 2) were administered daily. By ultrasound and luteinizing hormone measurements and / or changes in basal body temperature