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目的探讨MOFE患者的发病危险因素。方法采用1∶3配比病例对照研究方法。OR值及其95%CI的计算采用条件Logistic回归分析方法。结果经过多因素条件Logistic回归分析,感染、营养状态不良、免疫功能低下、肠道营养摄入障碍、精神障碍、精神打击、慢性病贫血、电解质紊乱、心律失常、心肌缺血发作、出血性脑卒中、晚期癌肿转移、手术或创伤等13个危险因素与MOFE的发生有明显的关联(OR及95%CI为:2.45～28.75及1.08～148.11,P<0.039～0.001)。结论对有上述因素的老年人群应视为MOFE高危对象,重点防范,并控制重要危险因素。
Objective To investigate the risk factors of MOFE. Methods 1: 3 ratio of case-control study. The OR value and its 95% CI were calculated using conditional logistic regression analysis. Results After multivariate Logistic regression analysis, the infection, malnutrition, immune dysfunction, intestinal malnutrition disorders, mental disorders, mental shock, chronic anemia, electrolyte imbalance, arrhythmia, myocardial ischemia, hemorrhagic stroke 13 patients with advanced cancer metastasis, surgery or trauma were significantly associated with the occurrence of MOFE (OR and 95% CI: 2.45-28.75 and 1.08-148.11, P <0.039-0.001). CONCLUSIONS: Elderly people with the above factors should be regarded as high risk MOFE targets with emphasis on prevention and control of important risk factors.