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目的:研究倍他乐克的不良反应最小用药剂量及临床特点。方法:回顾分析282例使用倍他乐克治疗患者的临床资料,汇总分析其不良反应发生情况、最小剂量及临床特点。结果:282例患者中,23例发生不良反应,最小剂量为50 mg/d,主要分布在老年患者。结论:倍他乐克用药剂量≥50 mg/d、长期使用、高龄、联合用药不当等将增加不良反应,临床应用中应严格掌握其适应证及用药剂量。
Objective: To study the minimum dose and clinical features of metoprolol. Methods: The clinical data of 282 patients treated with Betaloc were retrospectively analyzed. The adverse reactions, the minimum dose and the clinical features were summarized and analyzed. Results: Of the 282 patients, 23 had adverse reactions with a minimum dose of 50 mg / day, mainly in elderly patients. CONCLUSION: Betaloc should be used in patients with the dose ≥ 50 mg / d. Long-term use, advanced age and improper combination therapy will increase adverse reactions. Clinical indications and dosage should be strictly controlled.