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结直肠癌是临床常见的恶性肿瘤,其发病率居全球第3位。随着人口的老龄化和生活方式的演变,世界结直肠癌的发病率以每年2%的速度递增,而中国的增速则为3.9%,明显高于世界平均水平。肝脏是连接门静脉系统和腔静脉系统的桥梁,因其血窦的血液滤过作用,肝脏成为结直肠癌最先和最易侵及的器官。约25%的患者在初诊时即发现结直肠癌肝转移(colorectal liver metastases,CRLM),其余25%～50%的患者在后续治疗过程中最终发展为肝转移,肝转移是结直肠癌患者的首要死亡原因。近年来,CRLM的多学科综合治疗
Colorectal cancer is a common clinical malignancy, its incidence ranks third in the world. With population aging and lifestyle changes, the incidence of colorectal cancer in the world is increasing at a rate of 2% per annum, while that of China is 3.9%, significantly higher than the world average. The liver is a bridge between the portal system and the vena cava system. Due to the hemofiltration of the sinusoids, the liver becomes the first and most vulnerable organ for colorectal cancer. Approximately 25% of patients have colorectal liver metastases (CRLM) at the time of their first visit, and the remaining 25% to 50% of patients eventually develop liver metastases during follow-up, with liver metastases in patients with colorectal cancer The main cause of death. In recent years, CRLM’s multidisciplinary comprehensive treatment