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目的分析心脏原发性多发肿瘤的临床与病理特征。方法回顾性分析我院1981年1月至2007年12月经病理确诊的16例心脏原发性多发肿瘤患者的临床与病理资料,并进行电话随访。结果本组16例中,男8例,女8例;年龄1～64岁,平均(30.9±15.7)岁;病程1个月～15年,平均1.2年。15例行深低温体外循环下心脏直视手术摘除瘤体,其中3例行瓣膜置换;另1例行同种异体原位心脏移植。无围手术期死亡者,术后4例复发。超声心动图检查均示心脏占位病变,2例伴心包积液,7例漏诊。16例中黏液瘤9例,肉瘤2例,横纹肌瘤、浸润性脂肪瘤、淋巴管瘤、副神经节瘤、不典型纤维组织细胞瘤各1例。结论心脏原发性多发肿瘤以黏液瘤为主。手术难度大,术中要仔细探查,避免遗漏。术后复发率高,确诊后应及早手术。
Objective To analyze the clinical and pathological features of primary multiple heart tumors. Methods The clinical and pathological data of 16 patients with primary cardiac polyps diagnosed by pathology in our hospital from January 1981 to December 2007 were retrospectively analyzed and followed up by telephone. Results The group of 16 patients, 8 males and 8 females; aged 1 to 64 years, mean (30.9 ± 15.7) years of age; duration of 1 month to 15 years, an average of 1.2 years. Fifteen patients underwent open heart surgery under deep hypothermic cardiopulmonary bypass. Three patients underwent valve replacement and the other one underwent allogenic heart transplantation. No perioperative death, 4 cases of recurrence. Echocardiography showed heart lesions, 2 cases with pericardial effusion, 7 cases missed diagnosis. 16 cases of myxoma in 9 cases, 2 cases of sarcoma, rhabdomyoma, invasive lipoma, lymphangioma, paraganglioma, atypical fibrous histiocytoma in 1 case. Conclusion Myocardial primary multiple tumors are mainly myxomas. Surgery is difficult, intraoperative exploration to be careful to avoid missing. Postoperative recurrence rate, diagnosis should be early surgery.