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自然杀伤(NK)细胞能溶解肿瘤细胞,病毒感染细胞,细菌和预先没有致敏的正常细胞,如果这些细胞在保护机体对抗感染方面是一种早期的重要防御机制。那么在免疫系统成熟之前对婴儿的保护尤其重要。该研究测定了早产极低体重儿(VLBWI)、足月儿和成人的NK活性、NK细胞表型。对淋巴因子白细胞介素—2(IL—2)和γ—干扰素(γ—IFN)的生成和反应能力。发现NK活性在VLBWI比足月儿和成人为低。
Natural killer (NK) cells can lyse tumor cells, virus-infected cells, bacteria and normal cells that have not been previously sensitized, and are an early and important defense mechanism in protecting the body against infection. Then the protection of the baby before the immune system matures is especially important. The study determined NK activity, NK cell phenotype in preterm low birth weight (VLBWI), term term and adult. On lymphokine interleukin -2 (IL-2) and γ-interferon (γ-IFN) production and response capacity. NK activity was found to be lower in VLBWI than in term infants and adults.