自1980年3月以来,309名未分化性小细胞支气管癌(ASCB)患者进行随机维持(M)化疗或非维持(NM)化疗的试验之前,均曾接受了使病情缓解的诱导治疗,即由静脉注射长春新碱、阿霉素和环磷酰胺(VAC),每三周为一疗程,共6个疗程。肿瘤局限的患者还接受了纵隔放射治疗。在患者同意下,将无明显残余肿瘤患者随机分为两组,一组是在疾 Since March 1980, 309 patients with undifferentiated small cell bronchogenic carcinoma (ASCB) had received induction therapy for remission before undergoing random maintenance (M) chemotherapy or non-maintenance (NM) chemotherapy. Intravenous injection of vincristine, doxorubicin and cyclophosphamide (VAC) is a course of treatment every three weeks for a total of 6 courses. Patients with tumor limitations also received mediastinal radiation therapy. With the consent of the patient, patients with no apparent residual tumor were randomly divided into two groups.