Mitigation of sediment deposition in lined open channels is an essential issue in hydraulic engineering practice. Hence, the limiting velocity should be determined to keep the channel bottom clean from sedi-ment deposits. Recently, sediment transport modeling using various artificial intelligence (AI) techniques has attracted the interest of many researchers. The current integrated study highlights unique insight for modeling of sediment transport in sewer and urban drainage systems. A novel methodology based on the combination of sensitivity and uncertainty analyses with a machine leing technique is proposed as a tool for selection of the best input combination for modeling process at non-deposition conditions of sediment transport. Utilizing one to seven dimensionless parameters, 127 models are developed in the current study. In order to evaluate the different parameter combinations and select the training and testing data, four strategies are considered. Considering the densimetric Froude number (Fr) as the dependent parameter, a model with independent parameters of volumetric sediment concentration (CV) and relative particle size (d/R) gave the best results with a mean absolute relative error (MARE) of 0.1 and a root means square error (RMSE) of 0.67. Uncertainty analysis is applied with a machine leing technique to inves-tigate the credibility of the proposed methods. The percentage of the observed sample data bracketed by 95％predicted uncertainty bound (95PPU) is computed to assess the uncertainty of the best models.