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目的观察高压氧(HBO)在急性氮气中毒救治中的应用。方法 11例急性氮气中毒患者,均为男性,年龄24~54岁,平均年龄36.9岁。应用HBO联合综合性治疗。分析生物化学指标和酶谱情况,以及脑电图、心电图、头颅CT。结果氮气中毒患者经过10~15次HBO治疗后,临床症状完全消失。全部患者治疗前白细胞总数、中性粒细胞、血糖、乳酸脱氢酶、磷酸肌酸激酶、肌酸激酶同工酶升高,治疗后下降,而血钾降低,治疗后回升。脑电图、心电图、头颅CT等检查完全恢复正常,未留下明显后遗症状。结论氮气中毒是由于缺氧导致的单纯性窒息,早期应用HBO是治疗氮气中毒有效的手段,有助于减轻脑损伤。
Objective To observe the application of hyperbaric oxygen (HBO) in the treatment of acute nitrogen poisoning. Methods A total of 11 patients with acute nitrogen poisoning were male, aged from 24 to 54 years with a mean age of 36.9 years. HBO combined with comprehensive treatment. Analysis of biochemical indicators and zymogram, as well as EEG, ECG, cranial CT. Results Nitrogen poisoning patients after 10 to 15 HBO treatment, the clinical symptoms disappeared completely. All patients before treatment, the total number of leukocytes, neutrophils, blood glucose, lactate dehydrogenase, creatine phosphokinase, creatine kinase isoenzyme increased, decreased after treatment, and serum potassium decreased after treatment rose. EEG, ECG, CT and other tests completely returned to normal, leaving no obvious symptoms. Conclusions Nitrogen gas poisoning is a simple asphyxia caused by hypoxia. Early application of HBO is an effective treatment for nitrogen poisoning and helps to reduce brain injury.