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从侧脑室注射组织胺观察其对大鼠胃酸分泌影响的实验表明,组织胺有刺激胃酸分泌的作用,此作用可分别被H_1受体阻断剂苯海拉明和H_2 受体阻断剂甲氰咪胍部分阻断。提示了侧脑室注射组织胺增加胃酸分泌的效应是通过H_1和H_2受体实现的。
Histamine from the lateral ventricle injection of histamine to observe its effect on gastric acid secretion experiments show that histamine can stimulate the role of gastric acid secretion, which can be H_1 receptor antagonist diphenhydramine and H_2 receptor blocker cyanogen Mianyang partially blocked. It is suggested that the effect of intracerebroventricular injection of histamine on gastric acid secretion is mediated by H 1 and H 2 receptors.