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目的:观察益气化瘀法配合化疗治疗晚期非小细胞肺癌的临床效果,并分析肿瘤控制效果、患者生存质量。方法:将94例非小细胞肺癌晚期患者分为对照组、观察组各47例,其中对照组患者行常规化疗,观察组患者加用配合益气化瘀法治疗,观察比较两组患者近期生存质量情况,统计用药不良反应,评估近期肿瘤控制情况。结果:入院时患者生存质量评分组间无统计学差异(P>0.05),用药后观察组患者生存质量评分较高(P<0.05);观察组肿瘤控制率为61.7%,明显高于对照组的44.7%(P<0.05);化疗期间,观察组患者用药所致不良反应(白细胞下降、胃肠道反应、血小板下降)发生率低于对照组(P<0.05)。结论:益气化瘀法配合化疗治疗晚期非小细胞肺癌疗效较佳,患者疾病控制情况良好,生存质量明显提高,且用药安全性高,不良反应少,值得临床推广应用。
Objective: To observe the clinical effects of Yiqi Huayu method combined with chemotherapy in the treatment of advanced non-small cell lung cancer and to analyze the effect of tumor control and the quality of life of patients. Methods: Ninety-four patients with advanced non-small cell lung cancer were divided into control group and observation group (n = 47). The control group received routine chemotherapy and the observation group received combined therapy of Yiqi Huayu method. The recent survival of the two groups was observed Quality, statistical adverse drug reactions, assessment of recent tumor control. Results: There was no significant difference in the quality of life of patients on admission (P> 0.05), and the quality of life of observation group was higher after treatment (P <0.05). The tumor control rate in observation group was 61.7%, which was significantly higher than that in control group (P <0.05). The incidence of adverse reactions (leukopenia, gastrointestinal reaction, thrombocytopenia) in the observation group was lower than that in the control group during chemotherapy (P <0.05). Conclusion: Yiqi Huayu Decoction combined with chemotherapy is effective in treating advanced non-small cell lung cancer. The disease control is good, the quality of life is obviously improved, and the medication is safe and has few adverse reactions. It is worthy of clinical application.