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目的:探讨单核细胞/高密度脂蛋白胆固醇比值(MHR)与心脏X综合征(CSX)的关系。方法:收集2017-01-2017-08在我院就诊,被诊断为心脏X综合征的患者75例作为病例组,选择同期在我院体检中心体检的健康人75例作为对照组。记录病例组患者入院时及对照组人群的总胆固醇脂(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、中性粒细胞数、淋巴细胞数、单核细胞数,计算出MHR,两组间进行对比。结果:同对照组相比,CSX组高血压病比例升高,单核细胞数增多、MHR升高,差异有统计学意义(P均<0.05)。多因素Logistic回归分析结果显示:MHR(P=0.028,OR=2.054,95%CI:1.080~3.905)是CSX的危险因素。结论:MHR的升高与心脏X综合征的发生相关,是心脏X综合征的危险因素。升高的MHR可作为诊断心脏X综合征的参考指标之一。
Objective: To investigate the relationship between monocyte / high density lipoprotein cholesterol ratio (MHR) and cardiac X syndrome (CSX). Methods: Seventy-five patients who were diagnosed as cardiac syndrome X from 2017-01-2017-08 in our hospital were selected as the case group. 75 healthy people who were examined in our hospital during the same period were selected as the control group. The total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C), low density lipoprotein (LDL-C), neutrophil count , The number of lymphocytes, the number of monocytes, calculated MHR, compared between the two groups. Results: Compared with the control group, the proportion of hypertensive patients increased, the number of mononuclear cells increased, and the MHR increased in CSX group (P <0.05). Multivariate logistic regression analysis showed that MHR (P = 0.028, OR = 2.054, 95% CI: 1.080-3.905) was a risk factor for CSX. Conclusion: The increase of MHR is associated with the occurrence of cardiac X syndrome and is a risk factor of cardiac X syndrome. Elevated MHR can be used as a diagnostic indicator of cardiac X syndrome one of the indicators.