,Outcomes of balloon mitral valvuloplasty for rheumatic mitral stenosis during pregnancy

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Rheumatic mitral stenosis is the most common acquired valvular heart disease encountered during pregnancy.Balloon mitral valvuloplasty (BMV) is one of the treatment options if the symptoms are refractory to the medical management and the valve anatomy is suitable for balloon dilatation.Prospective studies on BMV and its effect on pregnancy outcomes and neonates are needed.Methods All pregnant women with severe symptomatic isolated mitral stenosis who underwent elective BMV in our institute from January 2000 to December 2018 were analyzed retrospectively.Clinical,haemodynamic and echocardiographic outcomes immediately after the procedure were analyzed.Results This study involved twenty-seven pregnant women in whom BMV was performed.The procedure was successful in 26 patients (96.29%).There were significant changes after BMV in the measured 2D MVA,pulmonary arterial systolic pressure and the mean left atrial pressure (P<0.01).Post-procedure follow-up showed an improvement in NYHA status by at least one class in 85.19% (25/27) patients.In the cases of mitral valve regurgitation,the area of mitral valve regurgitation increased significantly after the procedure (P<0.01).Four (19.05%) patients had a full-term normal vaginal delivery and seventeen (80.95%) underwent cesarean section for obstetric indications.Five patients had abortions after the procedure.After the procedure,only one patient had severe mitral regurgitation after the procedure and nine patients had moderate mitral regurgitation,and the rest had either no mitral regurgitation or mild mitral regurgitation.Symptomatic improvement was noted in all of the patients with on mateal and fetal complications except one case of mortality.Conclusion Percutaneous BMV is safe and effective in providing excellent symptomatic relief and hemodynamic improvement for pregnant patients with mitral stenosis.
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