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目的探讨氟西汀联合多潘立酮治疗功能性消化不良(FD)的临床疗效。方法将门诊及住院95人患FD的患者,随机分成治疗组和对照组,均予以多潘立酮治疗,治疗组加用氟西汀口服治疗。结果治疗8周后统计结果,治疗组与对照组疗效比较,差异有统计学意义(P<0.05),治疗组的复发率低于对照组(P<0.05)。结论氟西汀与多潘立酮联合使用可提高治疗功能性消化不良的疗效,减少复发率。
Objective To investigate the clinical efficacy of fluoxetine combined with domperidone in the treatment of functional dyspepsia (FD). Methods 95 outpatients and hospitalized patients with FD were randomly divided into treatment group and control group, were treated with domperidone, the treatment group plus fluoxetine oral treatment. Results After 8 weeks of treatment, the curative effect of the treatment group and the control group was statistically significant (P <0.05), and the recurrence rate of the treatment group was lower than that of the control group (P <0.05). Conclusions Combination of fluoxetine and domperidone can improve the curative effect of treating functional dyspepsia and reduce the recurrence rate.