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实验将30例严重骨质疏松和多发椎体骨折的妇女随机分两组行hPTH(1-34)循环治疗两年,14例皮下注射hPTH(1-34),50μg/d共28天,16例在皮下注射hPTH(1-34)28天后加用42天的降钙素,75U/d,剩下20天空白。三个月为一个周期,两年共完成8个周期。另外选取15例未用任何治疗的严重骨质疏松妇女作对照。对照组和实验组没有明显的差别,他们都有严重的骨质疏松,表现为多发的椎体压缩骨折和椎体骨密
Thirty patients with severe osteoporosis and multiple vertebral fractures were randomly divided into two groups and treated with hPTH (1-34) for two years. Hypophosphatemic acid (1-34) was administered subcutaneously in 14 cases for 28 days at a dose of 50 μg / d Example 28 days after subcutaneous injection of hPTH (1-34) plus 42 days of calcitonin, 75U / d, leaving 20 days blank. Three months for a period of two years to complete a total of eight cycles. In addition, 15 cases of severe osteoporosis women without any treatment were selected as controls. The control group and the experimental group no significant difference, they have severe osteoporosis, manifested as multiple vertebral compression fractures and vertebral bone density