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目的 研究碘硒防治后地方性甲状腺肿残留病例的病理变化。方法 甲状腺Ⅱ度肿大的残留病例共１７ 例，对其中的１１ 例作组织病理学研究。结果 １１ 例中男性６ 例，女性５ 例，年龄３２～７４ 岁，甲状腺肿的病程４～６４ 年。病理检查发现：结节性甲状腺肿３ 例，结节性甲状腺肿伴钙化１ 例，甲状腺腺瘤７ 例（其中甲状腺腺瘤伴出血、钙化者４ 例，甲状腺腺瘤囊化变１ 例）。结论 在地方性甲状腺肿残留病例中可能存在着结节性甲状腺肿，甲状腺腺瘤、甲状腺囊肿及其他甲状腺疾病。
Objective To study the pathological changes of endemic goiter after iodine-selenium prevention and treatment. Methods A total of 17 cases with enlarged thyroid Ⅱ degree histopathology were studied in 11 of them. Results 11 cases of 6 males and 5 females, aged 32 to 74 years, duration of goiter 4 to 64 years. Pathological examination revealed 3 cases of nodular goiter, 1 case of nodular goiter with calcification, and 7 cases of thyroid adenoma (thyroid adenoma with hemorrhage, calcification in 4 cases and thyroid adenoma with 1 case of enucleation). Conclusion There may be nodular goiter, thyroid adenoma, thyroid cyst and other thyroid diseases in endemic goiter residual cases.