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目的:探讨精神分裂症患者长期服药后内镜下成像与血清胃泌素特点方法:将自贡市第五人民医院精神科收治的60例有消化系统疾病的精神分裂患者按其服药疗程分为A组和C组各30例,自贡市第五人民医院综合科收治的长期服药的30例糖尿病或高血压患者分为B组.分别对其进行无痛胃镜检查和空腹血清胃泌素检测.结果:C组胆汁反流性胃炎、胃储留34.37%和30.21%明显高于A、B组(P<0.05),差异有显著性.C组血清胃泌素明显低于A组与B组(78.43 pg/mL±10.68 pg/mL vs 88.72pg/mL±11.35 pg/mL,90.14 pg/mL±9.57 pg/mL)(P<0.05),差异有显著性.结论:精神分裂症患者长期服药后易发生胆汁反流性胃炎、胃潴留,血清胃泌素降低.
Objective: To investigate the characteristics of endoscopic imaging and serum gastrin in schizophrenic patients after long-term medication.Methods: 60 schizophrenic patients with digestive system diseases admitted to Psychiatric Department of the Fifth People’s Hospital of Zigong City were divided into A 30 patients in group C and 30 patients in long-term medication for diabetes in patients admitted to the Fifth People’s Hospital of Zigong City were divided into group B. Patients were evaluated by gastroscopy and fasting serum gastrin respectively : C group reflux gastritis, gastric reserve 34.37% and 30.21% were significantly higher than A, B group (P <0.05), the difference was significant.The serum gastrin in group C was significantly lower than that in group A and group B 78.43 pg / mL ± 10.68 pg / mL vs 88.72 pg / mL ± 11.35 pg / mL, 90.14 pg / mL ± 9.57 pg / mL) (P <0.05) .Conclusion: After long-term administration of schizophrenia, Bile reflux gastritis prone, gastric retention, decreased serum gastrin.