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作者在3例神经损伤的病例中,手术前麻醉时使用琥珀胆硷后,瘫痪的肌肉出现了4～5分钟的收缩现象,作者指出此现象有助于鉴别神经损伤和肌腱断裂。按照神经肌肉传递方式的新理论,冲动到达运动神经终末时,神经末稍的小囊释放乙烯胆硷。后者增加肌膜的通透性,造成钠离子的大量涌入,产生终板的去极电位,结果电位低落使肌膜去极化而达到激发水平。
In three cases of neurological injury, paracentesis was observed in 4 to 5 minutes of contraction after the use of succinylcholine anesthesia before surgery. The authors point out that this phenomenon helps to identify nerve damage and tendon rupture. According to the new theory of neuromuscular transmission, when the impulse arrives at the motor nerve terminal, the terminal vesicles of the nerve release vinylcholine. The latter increase the permeability of the sarcolemma, resulting in a large influx of sodium ions, resulting in depolarization potential of the end plate, resulting in low potential so that the membrane depolarization to achieve the excitation level.