对１９９２～１９９７年住院的３６例原发性高尿酸血症肾病总结分析。其占同期原发性痛风的７５％，伴有关节损害者占８３％。据ＢＵＮ、Ｓｃｒ值，将患者分为非肾衰组与肾衰组。肾衰组合并高血压者显著高于非肾衰组；两组尿渗透压／血渗透压比值几乎均＜１．５；肾衰组血尿酸／血肌酐＞２．５仅４７％；尿尿酸排泄量肾衰组较非肾衰组显著减少。提示尿酸性肾病多数伴有关节炎，且肾功能损害进展缓慢，早期以肾小管功能损害为主。另肾衰时不能简单地根据血尿酸／血肌酐比值判断有无尿酸性肾病 Summary of 36 cases of primary hyperuricemic nephropathy hospitalized from 1992 to 1997. It accounts for 75% of primary gout over the same period, with 83% of those with joint damage. According to BUN, Scr values, the patients were divided into non-renal failure group and renal failure group. Renal failure combined with hypertension were significantly higher than non-renal failure group; two groups of urine osmolality / blood osmotic pressure ratio were almost <1.5; renal failure group serum uric acid / serum creatinine> 2.5 only 47%; uric acid Excretion of renal failure group was significantly reduced compared with non-renal failure group. Tip of the majority of patients with uric acid nephropathy associated with arthritis, and slow progress of renal dysfunction, early renal damage mainly. The other renal failure can not simply based on uric acid / serum creatinine ratio to determine whether there is no uric acid nephropathy