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目的:探究白色念球菌抗菌药物相关性腹泻的临床检验特征,为开展临床诊治工作提供重要的参考依据。方法:选取我院收治的100例抗菌药物相关性腹泻患者作为研究对象,按照患者受感染的细菌不同,对两组患者血钠水平、血钾水平、空腹状态下血糖水平、清蛋白水平以及抗菌类药物的使用和敏感等情况进行检查和对比分析。结果:白色念球菌感染组44例患者的血钠水平、血钾水平、空腹状态下的血糖水平都明显高于非白色念球菌感染组患者的,清蛋白水平低于非念球菌感染组患者的,差异具有显著的统计学意义(P<0.05)。同时,白色念球菌感染组患者对伊曲康唑、氟康唑、两性霉素等药物的耐药性明显低于非白色念球菌感染组患者的,同时药物的敏感性明显非念球菌感染组患者的,两者之间的差异具有显著的统计学意义(p<0.05).结论:对于抗菌药物相关性腹泻患者可以将粪便细菌培养作为主要的检查方法,同时在临床上应该注意抗生素的滥用。
Objective: To investigate the clinical features of Candida albicans antibiotic-associated diarrhea and provide important reference for carrying out clinical diagnosis and treatment. Methods: 100 cases of antibiotic-associated diarrhea admitted to our hospital were selected as research objects. According to the different bacteria of patients infected, the blood sodium level, serum potassium level, fasting blood glucose level, albumin level, Drug use and sensitivity of the situation such as inspection and comparative analysis. Results: Serum sodium level, serum potassium level and fasting blood glucose level in 44 patients with Candida albicans infection were significantly higher than those in non-Candida albicans infection group and albumin levels were lower than those in non-Candida infection group , The difference was statistically significant (P <0.05). At the same time, the drug resistance of Candida albicans infection group to itraconazole, fluconazole, amphotericin and other drugs was significantly lower than that of the non-Candida albicans infection group, and the drug sensitivity was significantly non-Candida infection group (P <0.05) .Conclusion: Bacteria culture in feces of patients with antibiotic-drug-related diarrhea can be used as the main method of examination, and at the same time, the abuse of antibiotics should be paid attention to clinically .