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目的 评价新鲜人羊膜在眼表重建手术中的临床价值。方法 用新鲜羊膜移植 ,治疗陈旧性睑球粘连、结膜囊缺失、复发性翼状胬肉、蚕蚀性角膜溃疡、热烧伤后角膜和结膜溶解等眼表疾病的连续病例19例 ( 2 1只眼 )。结果 19例患者的羊膜移植手术均为一次成功。平均随访 12 .5个月 ,羊膜移植片未见免疫排斥反应或溶解吸收。手术后 ,患者的睑球粘连松解 ,结膜囊形成 ,蚕蚀性角膜溃疡和复发性翼状胬肉在随访期间未见复发 ,角膜和结膜溶解未继续进展。结论 新鲜羊膜和保存的羊膜一样 ,可有效地重建角膜和结膜表面。新鲜羊膜具有取材简单 ,使用方便 ,费用低廉等优点 ,更适合于基层医院在眼表重建手术中使用。
Objective To evaluate the clinical value of fresh human amniotic membrane in the reconstruction of ocular surface. Methods Nineteen consecutive cases (21 eyes) were treated with fresh amniotic membrane transplantation for the treatment of ocular surface diseases such as old symblepharon, conjunctival sac missing, recurrent pterygium, Mooren ulcer, cornea and conjunctiva after thermal burn. ). Results 19 cases of amniotic membrane transplantation were successful. The average follow-up of 12.5 months, amniotic membrane graft no immune rejection or dissolution and absorption. After surgery, the patient’s symblepharon release, conjunctival sac formation, Mooren ulcer and recurrent pterygium recurrence during the follow-up period, the cornea and conjunctiva did not continue to dissolve. Conclusions Fresh amniotic membranes, like preserved amniotic membranes, can effectively reconstruct the corneal and conjunctival surfaces. Fresh amniotic membrane with a simple, easy to use, low cost and other advantages, more suitable for primary hospitals in the ocular surface reconstruction surgery.