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目的:对比高通量与低通量对血液透析患者的微炎症及营养状况的影响。方法:2013年8月至2017年2月选择在本院诊治的78例尿毒症患者作为研究对象,根据随机数字表法分为观察组与对照组各39例,对照组给予低通量透析,观察组高通量透析,记录微炎症及营养状况变化情况。结果:治疗后,观察组患者CRP水平降低,对照组升高,观察组与治疗前相比,两组间比较差异有统计学意义(P<0.05);治疗后观察组的白蛋白浓度为(35.03±3.19)g/L,明显高于对照组(31.99±7.11)g/L,两组间比较差异有统计学意义(P<0.05)。结论:相对于低通量,高通量血液透析在尿毒症患者中的应用能改善患者的微炎症及营养状况,有很好的应用价值。
Objective: To compare the effects of high-flux and low-flux on micro-inflammation and nutritional status in hemodialysis patients. Methods: From August 2013 to February 2017, 78 patients with uremia diagnosed and treated in our hospital were selected as study subjects. According to the random number table, 39 cases were divided into observation group and control group. The control group was given low-flux dialysis, Observation group high-throughput dialysis, record micro-inflammation and nutritional status changes. Results: After treatment, the level of CRP in the observation group decreased and the control group increased. The difference between the two groups was statistically significant (P <0.05). The albumin concentration in the observation group was ( 35.03 ± 3.19) g / L, which was significantly higher than that of the control group (31.99 ± 7.11) g / L, with significant difference between the two groups (P <0.05). Conclusion: Compared with low-flux, high-throughput hemodialysis in patients with uremia can improve the patient’s micro-inflammation and nutritional status, has a good value.