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氟啶酸(enoxacin)是一种新合成的喹诺酮类广谱抗生素,在体外有很好的抗淋球菌活性。对90％PPNG和非PPNG菌株的MIC均<0.06μg/ml。本文报告用氟啶酸和头孢三嗪噻肟治疗无并发症淋病的多中心随机对照研究。受试者均为16岁以上在美国3个州的SID门诊就诊的成年病人,共152例,男119例,女33例。男性作尿道分泌物涂片,找到细胞内革兰阴性双球菌;女性作宫颈粘膜涂片找到细胞内革兰阴性双球菌,并于最近有淋球菌培养阳性而未经治疗或最近(14天内)与已确诊为淋球菌感染的性侣有性交史。病史提示有性接触史者加作直肠和咽部标本培养,同时作淋球菌药物敏感试验和衣原体培养。疗
Enoxacin is a newly synthesized quinolone broad-spectrum antibiotic and has good anti-gonococcal activity in vitro. MICs for both 90% PPNG and non-PPNG strains were <0.06 μg / ml. This article reports a multicenter, randomized controlled study of gonorrhea and ceftriaxone for the treatment of uncomplicated gonorrhea. Subjects were all adult patients over the age of 16 who were referred to the SID clinic in three U.S. states, including 119 males and 33 females. Men make urethral smears to find intracellular gram-negative diplococci; women make intracellular smegma-negative diphosphatids for cervical mucosal smear and have recently been gonococcal-positive for untreated or recently treated (within 14 days) Has been diagnosed with gonococcal infection have sex history. History suggests that history of sexual contact plus rectal and pharyngeal specimen culture, at the same time for Neisseria gonorrhoeae drug sensitivity test and chlamydia culture. Treatment