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以氯化血红素为原料经加成、脱铁、醚化及水解合成了７个新的血卟啉乙二醇醚类化合物（１ａ～ｇ），１ａ～ｇ在Ｄ２Ｏ中对ＮＡＤＰＨ光氧化作用的敏化效应均高于ＨｐＤ，１ｂ对小鼠Ｓ１８０肉瘤的光动力损伤作用明显高于ＨｐＤ。
Seven new hematoporphyrin glycol ethers (1a ~ g) were synthesized by addition, deferrization, etherification and hydrolysis of hemin with 1a ~ g photooxidation of NADPH in D2O Sensitization effect were higher than HpD, 1b photodynamic damage in S180 sarcoma was significantly higher than HpD.