最近,随影像学诊断技术的迅速发展,使诊断的准确性得到了显著提高,相当小的病灶也能发现;若能结合包括脏器特异性抗原等在内的广义上的肿瘤标记物和生化学检测,则许多肿瘤都能做出正确的诊断。但现在仍有不得不做出原发不明癌这一临床诊断的病例。这些病例有必要通过剖检详细观察确定原发灶,并深入探索其生前难以发现原发灶的原因。遗憾的是,有关原发不明癌的病理学资料非常少见。 Recently, with the rapid development of imaging diagnostic technology, the accuracy of diagnosis has been significantly improved, and relatively small lesions can be found; if it can be combined with a broad range of tumor markers and organisms including organ-specific antigens, etc. With chemical tests, many tumors can make the right diagnosis. However, there are still cases in which clinical diagnosis of primary unexplained cancer has to be made. In these cases, it is necessary to observe the primary lesion through detailed observations and to explore in depth the reasons why it is difficult to find the primary lesion during his lifetime. Unfortunately, pathological data about the primary unknown cancer is very rare.