肾小管性酸中毒(以下简称RTA),1936年首先由Lightwood报道。本病并非罕见。其临床表现多种多样,常易误诊。轻者可隐潜不发,重者常有代谢性酸中毒,水电解质紊乱,骨骼病变,尿路结石和尿路感染,甚而产生严重并发症如骨骼畸形、病理骨折、肾结石、肾钙化及慢性肾功能衰竭 Renal tubular acidosis (hereinafter referred to as RTA), first reported by Lightwood in 1936. The disease is not uncommon. A variety of clinical manifestations, often misdiagnosed. Light can not conceal potential, severe metabolic acidosis often, water and electrolyte disorders, bone disease, urinary tract stones and urinary tract infections, and even have serious complications such as skeletal deformities, pathological fractures, kidney stones, renal calcification and Chronic renal failure