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目的 探讨介入治疗在小儿肝母细胞瘤综合治疗中的地位及适应证。方法 对估计不能切除的肿瘤施以碘油化疗药物栓塞 ,然后再外科手术 ,9例中有 7例施行了肝叶切除 ,右三叶 3例 ,右半肝 2例 ,左半肝 2例。结果 介入后 ,小儿副反应轻 ,肿瘤体积缩小 ,6例AFP值下降。未施手术1例介入后肺转移死亡 ,探查术 1例后改肝移植术后死亡 ,肝叶切除 7例中 ,死亡 5例 ( 3例复发 ,1例脑转移 ,1例肝功能衰竭 )存活 2例健在。结论 介入治疗可以使某些不能Ⅰ期切除的肝母细胞瘤有了手术切除的机会 ,但要掌握适应证和方法
Objective To investigate the status and indications of interventional therapy in hepatoblastoma in children. Methods Totally resected tumors were treated with lipiodol chemoembolization and then surgically. Seven of the nine patients underwent hepatectomy. There were 3 patients with right trichome, 2 with right and 2 with left hemiliver. Results After intervention, pediatric side effects, tumor size decreased, 6 cases of AFP value decreased. One patient who did not receive surgery had died of lung metastasis after intervention, one died after liver transplantation after probing and 5 patients died of hepatectomy (3 patients relapsed, 1 patient had brain metastasis and 1 patient had liver failure). 2 cases are alive. Conclusion Interventional treatment can make some resection of hepatoblastoma can not be a chance of surgical resection, but to grasp the indications and methods