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目的:分析药物干预在儿童抗生素相关性腹泻(AAD)中的应用效果。方法:回顾性分析我院2011年2月至2012年2月收治的78例儿童呼吸道感染患者的临床资料。对确诊为AAD的68例患儿实施药学干预措施,比较分析患儿干预前、后的抗生素使用情况。结果:对68例患儿实施药学干预以后,不合理应用抗生素的情况得到有效改善,AAD的发生概率从干预前的40.03%直接下降至8.64%,药学干预前、干预后相比,差异明显,具有统计学意义(P<0.05)。结论:实施有效的药学干预可明显降低儿童AAD的发生率,提高临床治疗效果。
Objective: To analyze the effect of drug intervention in children with antibiotic-associated diarrhea (AAD). Methods: The clinical data of 78 children with respiratory tract infection admitted to our hospital from February 2011 to February 2012 were analyzed retrospectively. Pharmacological interventions were performed on 68 children diagnosed with AAD and their antibiotic use was compared before and after intervention. Results: After 68 cases of children were treated with antibiotics, the unreasonable use of antibiotics was effectively improved. The incidence of AAD was directly decreased from 40.03% before intervention to 8.64%. There was significant difference between before and after the intervention, Statistically significant (P <0.05). Conclusion: The implementation of effective pharmacological intervention can significantly reduce the incidence of AAD in children and improve the clinical effect.