1病例报告患者男,45岁。因腹痛腹泻给予口服呋喃唑酮治疗,每次0.1g,每天4次。服药至第4天,患者饮白酒约100ml,20min后自觉颜面发热,未引起重视,继续饮白酒300ml,约1.5h后出现胸闷、心悸。查体:呼吸24次/min,血压106/60mmHg(平时150/100mmHg),心率126/min,律齐;颜面、前胸潮红,球结膜充血,神经系统未见异常。考虑为服用呋喃唑酮后饮酒引起的双硫仑样反应。立即给予吸氧,地塞米松10mg、维生素C 1 case report Male patient, 45 years old. Due to abdominal pain diarrhea given oral furazolidone treatment, each 0.1g, 4 times a day. Medication to the first 4 days, patients drink about 100ml of liquor, conscious facial fever after 20min, did not pay attention, continue to drink liquor 300ml, about 1.5h after chest tightness, palpitations. Examination: breathing 24 times / min, blood pressure 106/60 mmHg (usually 150 / 100mmHg), heart rate 126 / min, law Qi; face, front chest flush, conjunctival hyperemia, no abnormalities in the nervous system. Consider the disulfiram-like response to drinking after taking furazolidone. Immediately give oxygen, dexamethasone 10mg, vitamin C.