婴儿肝炎综合征(HIS)。是指1岁以内的婴儿(包括新生儿)因感染、先天性代谢异常、以及肝内外胆道阻塞或畸形等原因引起肝脏炎症的临床症候群,以黄疸、肝、脾肿大和肝功能异常为特征。在日本,则指原因不明于新生儿期发病的婴幼儿肝内胆汗淤滞性肝炎,并按有无肝细胞肿胀变性而划分为狭义和广义的婴儿肝炎综合征。一般而言,狭义的婴儿肝炎综合征是指由感染所致的肝炎,广义的婴儿肝炎综合征则包括婴幼儿期的一切肝脏损害。黄疸一般在生后4周出现,少数迟至6个月时出现,同时伴有尿色加深,大便颜色变浅或呈灰白色,多有肝脏肿大,50%病人伴有脾脏肿大。病人可有生长 Infant Hepatitis Syndrome (HIS). Refers to clinical syndromes of liver inflammation caused by infections, congenital metabolic abnormalities, and obstruction or abnormalities of biliary and internal and external biliary tract in infants (including newborns) within 1 year old, and is characterized by jaundice, liver, splenomegaly and abnormal liver function. In Japan, refers to the cause is unknown in infants with neonatal onset of intrahepatic biliary stasis hepatitis, and with or without hepatocellular swelling and degeneration is divided into narrow and broad sense of the infant hepatitis syndrome. In general, the narrow definition of infant hepatitis syndrome is caused by infection of hepatitis, generalized infant hepatitis syndrome, including all infant liver damage. Jaundice usually occurs 4 weeks after birth, a few appear as late as 6 months, accompanied by deepened urine, stool color lighter or gray, and more liver enlargement, 50% of patients with splenomegaly. The patient can grow