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[目的]探讨湛江市流感流行规律,以做好流感预防控制工作。[方法]通过流感监测系统和法定传染病监测系统,对湛江市2005~2006年流感进行流行病学、病原学、血清学监测。[结果]2005~2006年流感监测点流感样病例分别为9375和10086例,分别占门诊总病例数的10.1%和5.8%。发生13起流感暴发,发病190例,分离到103株流感病毒。其中,2005年上半年以H3N2亚型为优势毒株(21株),下半年B型为优势毒株(18株);2006年以H1N1为优势毒株(54株)。正常人群流感流行株抗体的总阳性率为1.0%~86.0%。[结论]不同型别的毒株表现出交替占优势的特征,人群流感抗体水平的消长与优势株的型别一致。
[Objective] To explore the epidemic law of influenza in Zhanjiang to prevent and control influenza. [Methods] Influenza epidemiology, etiology and serology were monitored in Zhanjiang City from 2005 to 2006 through influenza surveillance system and legal infectious disease surveillance system. [Results] The number of flu-like cases in influenza surveillance sites in 2005-2006 were 9375 and 10086 respectively, accounting for 10.1% and 5.8% of the total number of outpatients. Thirteen flu outbreaks occurred, with 190 cases and 103 influenza viruses isolated. Among them, H3N2 subtypes were the dominant strains (21 strains) in the first half of 2005 and the dominant strains (18 strains) in the second half of the year. In 2006, H1N1 was the dominant strain (54 strains). The prevalence of influenza antibodies in normal population was 1.0% ~ 86.0%. [Conclusion] The strains of different genotypes showed the characteristics of alternating predominance. The population growth and decline of influenza antibody level was consistent with that of dominant strains.